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Volume 29 Issue 2
Sep.  2013
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Research of polymers used in fabrication of biochip

  • 1.

    College of Laser Engineering, Beijing University of Technology, Beijing 100022, China

  • Corresponding author: CHEN Tao, chentao@bjut.edu.cn
  • Received Date: 2004-03-07
    Accepted Date: 2004-05-27
  • Using excimer laser to manufacture polymer materials can get more ideal biochips.Considering the needed performances of materials used in fabrication of biochips,PMMA and PC's properties are compared.These properties involve in the transmittance of light waves of different wavelengths.The micro-structure of polymer materials after micromachined by excimer laser,the correlation of the ablation depth per pulse with different fluences of excimer laser for different polymers is measured.The energy of KrF excimer laser can be totally absorbed by PMMA and PC,therefore micromachining of biochip can be done by using excimer laser on PMMA and PC's surfaces.The influence on detection quality of PMMA is smaller than PC.The ablation depth per pulse of PMMA to excim er laser is higher than PC under the same fluence.PMMA is manufactured more easily but the quality of micro-structure ablated is worse than PC because of different reaction mechanics to excimer laser.
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    ROBERTS M A,ROSSIER J S,BERCIER P et al.UV laser machined polymer substrates for the development of microdiagnostic systems[J].Analy Chem,1997,69(11):2035～2042.
    [2]

    TRUCKENMÜLLER R,RUMMLER Z,SCHALLER T et al.Low-cost thermoforming of micro fluidic analysis chips[J].Journal of Micromechanics and Microengineering,2002,12(4):375～379.
    [3] 章吉良,周勇,陈迪.LIGA技术在医疗器械制备中的应用[J].微细加工技术,1998(3):63～71.
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    CUI L,ZHANG T,MORGAN H.Optical particle detection integrated in a dielectrophoretic lab-on-a-chip[J].Journal of Micromechanics and Microengineering,2002,12(1):7～12.
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  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Research of polymers used in fabrication of biochip

    Corresponding author: CHEN Tao, chentao@bjut.edu.cn
  • 1. College of Laser Engineering, Beijing University of Technology, Beijing 100022, China
  • Received Date: 2004-03-07
  • Accepted Date: 2004-05-27
  • Available Online: 2005-03-25

Abstract: Using excimer laser to manufacture polymer materials can get more ideal biochips.Considering the needed performances of materials used in fabrication of biochips,PMMA and PC's properties are compared.These properties involve in the transmittance of light waves of different wavelengths.The micro-structure of polymer materials after micromachined by excimer laser,the correlation of the ablation depth per pulse with different fluences of excimer laser for different polymers is measured.The energy of KrF excimer laser can be totally absorbed by PMMA and PC,therefore micromachining of biochip can be done by using excimer laser on PMMA and PC's surfaces.The influence on detection quality of PMMA is smaller than PC.The ablation depth per pulse of PMMA to excim er laser is higher than PC under the same fluence.PMMA is manufactured more easily but the quality of micro-structure ablated is worse than PC because of different reaction mechanics to excimer laser.

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